Description

(6S)-5,18-Didehydro-5,6,7,8,11,12-Hexahydroretinol is a specific, high-purity stereoisomer of a hydrogenated retinol derivative, offering a stable and potent form of vitamin A activity for advanced research and development. This compound is critical for applications requiring precise molecular structure and consistent biological activity, where standard retinol or its esters may not suffice. It is primarily utilized by researchers and formulators in the pharmaceutical, nutraceutical, and high-end cosmetic industries for developing novel therapeutics, targeted supplements, and advanced skincare solutions.

Application

• Pharmaceutical Research & Development: As a key intermediate or reference standard in the synthesis of novel retinoid-based drugs targeting dermatological conditions, oncology, and metabolic disorders.
• Advanced Nutraceutical Formulations: For the development of high-potency, specialty vitamin A supplements where specific isomer activity and stability are paramount.
• Cosmeceutical & Skincare Actives: Incorporated into premium anti-aging, skin-renewal, and regenerative cosmetic products for its potent biological activity on skin cells.
• Biochemical Research: Used as a ligand or substrate in studies of retinoid receptors (RARs, RXRs), cellular differentiation, and gene expression pathways.
• Reference Standard & Analytical Testing: Serves as a high-purity certified reference material (CRM) for quality control and assay development in analytical laboratories.
• Specialty Chemical Synthesis: Acts as a sophisticated building block for the chemical synthesis of complex retinoid analogs and derivatives.

Basic Information

Product Name	(6S)-5,18-Didehydro-5,6,7,8,11,12-Hexahydroretinol
CAS No.	69903-57-7
Molecular Formula	C20H30O
Molecular Weight	286.45 g/mol
Synonyms	(6S)-5,18-Didehydro-5,6,7,8,11,12-hexahydroretinol; (6S)-5,18-Didehydro-5,6,7,8,11,12-hexahydrovitamin A alcohol; all-trans-(6S)-5,18-Didehydro-5,6,7,8,11,12-hexahydroretinol; Hexahydroretinol derivative; Vitamin A derivative, hydrogenated; (6S)-Hexahydroretinol
EINECS	Contact for details

Quality Control

Our (6S)-5,18-Didehydro-5,6,7,8,11,12-Hexahydroretinol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing specific batch results are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at 2-8°C under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. The container should be kept in a cool, dry, and well-ventilated area away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%
Solvent Residues (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.