Description

2A,3,5,6,11A,11B-Hexahydro-3-Hydroxy-2A,6,10-Trimethyl-3-(1-Methylpropyl)-6,9-Epoxy-2H-1,4-Dioxacyclodeca[Cd]Pentalene-2,7(4Ah)-Dione is a complex, high-purity macrocyclic lactone derivative of significant interest in advanced organic synthesis. This compound serves as a critical chiral intermediate and building block for the development of novel pharmacologically active molecules. It is primarily sought after by research institutions and pharmaceutical R&D departments engaged in the synthesis of complex natural product analogs and new chemical entities.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of novel macrocyclic drugs and complex natural product derivatives.
• Organic Synthesis Research: Valuable building block for constructing complex polycyclic ether and lactone frameworks in academic and industrial research.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and the development of new therapeutic agents targeting specific biological pathways.
• Asymmetric Synthesis: Employed as a substrate or template in catalytic asymmetric reactions due to its defined stereocenters.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	2A,3,5,6,11A,11B-Hexahydro-3-Hydroxy-2A,6,10-Trimethyl-3-(1-Methylpropyl)-6,9-Epoxy-2H-1,4-Dioxacyclodeca[Cd]Pentalene-2,7(4Ah)-Dione
CAS No.	69883-96-1
Molecular Formula	C₂₀H₂₈O₆
Molecular Weight	364.43 g/mol
Synonyms	6,9-Epoxy-2H-1,4-dioxacyclodeca[cd]pentalene-2,7(4aH)-dione, hexahydro-3-hydroxy-2a,6,10-trimethyl-3-(1-methylpropyl)-, (2aR,3S,4aS,6R,9S,11aR,11bS)-rel-; (rel)-(2aR,3S,4aS,6R,9S,11aR,11bS)-Hexahydro-3-hydroxy-2a,6,10-trimethyl-3-(1-methylpropyl)-6,9-epoxy-2H-1,4-dioxacyclodeca[cd]pentalene-2,7(4aH)-dione; A derivative of Aflatrem; Contact for additional trade names and abbreviations.
EINECS	Contact for details

Quality Control

Our high-purity grade of this advanced intermediate is produced under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC for purity and chiral analysis to confirm stereochemical integrity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive). For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 98.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.