Description

3-Cyano-2,4-Dichloroquinoline is a high-value, multi-functional heterocyclic building block characterized by its cyano and chloro substituents. This compound matters for its role as a critical intermediate in the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing advanced quinoline-based scaffolds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other biologically active quinoline derivatives.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, leveraging the quinoline core's bioactivity.
• Material Science Research: Serves as a building block for creating organic electronic materials, ligands for metal-organic frameworks (MOFs), and fluorescent dyes.
• Chemical Biology & Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and library synthesis for drug discovery programs.
• Catalyst & Ligand Development: Utilized to synthesize novel nitrogen-containing ligands for transition metal catalysis.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	3-Cyano-2,4-Dichloroquinoline
CAS No.	69875-54-3
Molecular Formula	C10H4Cl2N2
Molecular Weight	223.06 g/mol
Synonyms	2,4-Dichloro-3-cyanoquinoline; 3-Cyano-2,4-dichloroquinoline; Quinoline, 3-cyano-2,4-dichloro-; 2,4-Dichloroquinoline-3-carbonitrile; 69875-54-3
EINECS	Contact for details

Quality Control

Our 3-Cyano-2,4-Dichloroquinoline is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality parameters. Our commitment to cGMP principles and ISO-aligned processes guarantees a reliable supply for your most demanding applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.