Description

2-Chloro-4-Hydroxyquinoline-3-Carbonitrile is a versatile and high-value heterocyclic building block with significant synthetic utility. This compound is a key intermediate in the synthesis of complex molecules, particularly in the development of active pharmaceutical ingredients (APIs) and advanced agrochemicals. It is essential for research and production in the pharmaceutical, agrochemical, and fine chemical industries, where its unique quinoline scaffold enables the creation of novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various quinoline-based drug candidates, including potential antimicrobial, anticancer, and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the development of novel pesticides, herbicides, and fungicides, leveraging its bioactive quinoline core.
• Organic Synthesis Building Block: Serves as a versatile scaffold for constructing complex heterocyclic compounds in academic and industrial research laboratories.
• Material Science Research: Investigated for the development of organic semiconductors, fluorescent dyes, and other functional materials due to its electron-accepting properties.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical testing, method development, and quality control in regulatory and R&D settings.

Basic Information

Item	Details
Product Name	2-Chloro-4-Hydroxyquinoline-3-Carbonitrile
CAS No.	69875-52-1
Molecular Formula	C10H5ClN2O
Molecular Weight	204.61 g/mol
Synonyms	2-Chloro-4-hydroxyquinoline-3-carbonitrile; 4-Hydroxy-2-chloroquinoline-3-carbonitrile; 3-Cyano-2-chloro-4-hydroxyquinoline; 2-Chloro-4-oxo-1,4-dihydroquinoline-3-carbonitrile; Quinoline-3-carbonitrile, 2-chloro-4-hydroxy-; 69875-52-1
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Hydroxyquinoline-3-Carbonitrile is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in regulated environments, including cGMP for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.