Description

4-(5-Mercapto-1,3,4-oxadiazol-2-yl)phenol is a specialized heterocyclic phenolic compound featuring a reactive mercapto group, making it a valuable multifunctional building block for advanced synthesis. Its unique molecular architecture, combining a phenol moiety with a 1,3,4-oxadiazole ring, enables its use in creating materials with tailored properties. This intermediate is primarily sought by researchers and manufacturers in the pharmaceutical, agrochemical, and polymer industries for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting enzymes or receptors where the phenol and thiol groups can be utilized for molecular recognition and binding.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators, where the oxadiazole ring contributes to biological activity.
• Polymer Modification & Additives: Acts as a functional monomer or cross-linking agent to introduce antioxidant, UV-stabilizing, or metal-chelating properties into specialty polymers and coatings.
• Ligand for Metal Complexation: The mercapto and phenolic hydroxyl groups make it a potential chelating agent for creating catalysts or metal-organic frameworks (MOFs).
• Material Science Research: Investigated for use in organic electronics, such as in the development of charge-transport materials or sensors, due to its conjugated system.
• Bioconjugation Chemistry: The reactive thiol group can be used for site-specific labeling or coupling of biomolecules in diagnostic and biochemical applications.

Basic Information

Product Name	4-(5-Mercapto-1,3,4-oxadiazol-2-yl)phenol
CAS No.	69829-90-9
Molecular Formula	C8H6N2O2S
Molecular Weight	194.21 g/mol
Synonyms	2-(4-Hydroxyphenyl)-5-mercapto-1,3,4-oxadiazole; 5-(4-Hydroxyphenyl)-1,3,4-oxadiazole-2-thiol; 4-(2-Mercapto-1,3,4-oxadiazol-5-yl)phenol; Phenol, 4-(5-mercapto-1,3,4-oxadiazol-2-yl)-; 5-(4-Hydroxy-phenyl)-[1,3,4]oxadiazole-2-thiol; 2-(p-Hydroxyphenyl)-5-mercapto-1,3,4-oxadiazole
EINECS	Contact for details

Quality Control

Our production of 4-(5-Mercapto-1,3,4-oxadiazol-2-yl)phenol adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques, including HPLC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support cGMP-compliant manufacturing for advanced research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound may be light-sensitive and should be handled under an inert atmosphere for long-term storage to prevent oxidation of the mercapto group. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.