Description

n-Carbobenzoxy-1,5-Diaminopentane Hydrochloride is a protected diamine derivative, primarily serving as a critical building block in organic synthesis and peptide chemistry. Its value lies in providing a stable, reactive intermediate for the controlled elongation of molecular chains, particularly in the synthesis of complex bioactive molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require high-purity intermediates for advanced R&D and production.

Application

• Peptide Synthesis: A key protected intermediate for the controlled introduction of a pentamethylene diamine spacer in solid-phase and solution-phase peptide synthesis.
• Linker Chemistry: Used in the preparation of bifunctional cross-linking agents and spacers for bioconjugation, antibody-drug conjugates (ADCs), and polymer chemistry.
• Pharmaceutical Intermediates: Serves as a precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing polyamine structures.
• Organic Synthesis Building Block: Employed in the synthesis of heterocyclic compounds, macrocycles, and other complex organic molecules requiring a protected diamine functionality.
• Biomaterial Functionalization: Utilized to introduce amine-reactive sites onto surfaces, nanoparticles, or polymers for subsequent biomolecule attachment.
• Research & Development: A valuable reagent for academic and industrial research in medicinal chemistry and chemical biology.

Basic Information

Product Name	n-Carbobenzoxy-1,5-Diaminopentane Hydrochloride
CAS No.	69747-36-0
Molecular Formula	C₁₃H₂₁ClN₂O₂
Molecular Weight	272.77 g/mol
Synonyms	N5-[(Benzyloxy)carbonyl]-1,5-pentanediamine hydrochloride; Nα-Cbz-1,5-diaminopentane hydrochloride; Cbz-DAP HCl; 1,5-Diaminopentane, N5-carbobenzoxy-, hydrochloride; Z-1,5-Diaminopentane hydrochloride; (5-Amino-1-{[(benzyloxy)carbonyl]amino}pentyl)azanium chloride; N-Carbobenzoxycadaverine hydrochloride
EINECS	Contact for details

Quality Control

Our n-Carbobenzoxy-1,5-Diaminopentane Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, to ensure it meets high-grade specifications suitable for research and synthesis applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.