Description

4-[(Trifluoroacetyl)Oxy]Benzoic Acid is a high-value, multifunctional chemical intermediate characterized by its benzoic acid core modified with a reactive trifluoroacetyl ester group. This unique structure makes it a critical building block for synthesizing advanced materials and specialty compounds where the introduction of fluorine atoms and carboxylic acid functionality is required. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced polymer industries seeking to develop products with enhanced properties such as metabolic stability, lipophilicity, and thermal resistance.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring fluorinated motifs to improve bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the trifluoromethyl group can enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Acts as a building block for fluorinated monomers and polymers used in electronic displays and organic light-emitting diodes (OLEDs) due to its ability to influence molecular polarity and alignment.
• Advanced Polymer Modifier: Incorporated into specialty polymers to impart unique surface properties, chemical resistance, and thermal stability.
• Cross-coupling Reagent: Utilized in organic synthesis, such as Suzuki or Heck cross-coupling reactions, as a protected or activated form of 4-hydroxybenzoic acid.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D in medicinal chemistry and material science for creating novel fluorinated compounds.

Basic Information

Product Name	4-[(Trifluoroacetyl)Oxy]Benzoic Acid
CAS No.	69745-79-5
Molecular Formula	C9H5F3O4
Molecular Weight	234.13 g/mol
Synonyms	4-(Trifluoroacetoxy)benzoic Acid; Benzoic acid, 4-[(trifluoroacetyl)oxy]-; p-(Trifluoroacetoxy)benzoic Acid; 4-Carboxyphenyl trifluoroacetate; Trifluoroacetic acid 4-carboxyphenyl ester
EINECS	Contact for details

Quality Control

Our 4-[(Trifluoroacetyl)Oxy]Benzoic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee reliable performance in your processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.