Description

(R)-6,7-Dihydro[1,3]Benzodioxolo[5,6-C]-1,3-Dioxolo[4,5-I]Phenanthridin-6-Ol is a high-purity, chiral alkaloid derivative belonging to the phenanthridine class, characterized by its complex polycyclic structure incorporating multiple dioxole groups. This compound is a critical chiral building block and reference standard for advanced pharmaceutical research and development, particularly in the synthesis of novel bioactive molecules. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors who require high-fidelity intermediates for asymmetric synthesis, process development, and analytical method validation.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the research and synthesis of potential therapeutic agents, including alkaloid-based drugs.
• Asymmetric Catalysis Research: Used as a sophisticated ligand or substrate in the development and study of new asymmetric catalytic reactions.
• Analytical Reference Standard: Employed as a high-purity standard in HPLC, LC-MS, and NMR for method development, validation, and quality control of related compounds.
• Medicinal Chemistry & SAR Studies: Provides a complex molecular scaffold for structure-activity relationship (SAR) studies to explore new biological targets.
• Fine Chemical Synthesis: Acts as a specialized building block for the multi-step synthesis of complex natural product analogs and other high-value fine chemicals.
• Academic & Institutional Research: Utilized in university and institutional labs for advanced studies in organic synthesis, natural product chemistry, and chemical biology.

Basic Information

Product Name	(R)-6,7-Dihydro[1,3]Benzodioxolo[5,6-C]-1,3-Dioxolo[4,5-I]Phenanthridin-6-Ol
CAS No.	69735-28-0
Molecular Formula	C18H13NO5
Molecular Weight	323.30 g/mol
Synonyms	(R)-6-Hydroxy-6,7-dihydro[1,3]benzodioxolo[5,6-c][1,3]dioxolo[4,5-i]phenanthridine; (R)-Homolaudanosine; (R)-Laudanosine Derivative; (R)-Tetrahydropalmatrubine; (R)-THP; (R)-6,7-Dihydro-6-hydroxy[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]benzofuro[2,3-h]isoquinoline; (R)-Phenanthridine Alkaloid Derivative
EINECS	Contact for details

Quality Control

Our (R)-6,7-Dihydro[1,3]Benzodioxolo[5,6-C]-1,3-Dioxolo[4,5-I]Phenanthridin-6-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment. We can supply material compliant with various pharmacopeial standards upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (R-isomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.