Description

D-Aspartic Acid Dimethyl Ester Hydrochloride is a protected derivative of the non-essential amino acid D-aspartic acid, widely utilized as a key chiral building block in organic synthesis. This compound matters for its role in introducing the D-aspartate moiety into complex molecules, enabling the production of peptides and other bioactive compounds with specific stereochemistry. Pharmaceutical researchers and fine chemical manufacturers need it for the development of active pharmaceutical ingredients (APIs), peptide hormones, and advanced research chemicals.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate D-aspartic acid residues.
• Biochemical Research: Serves as a precursor or standard in metabolic pathway studies and neurological research.
• Asymmetric Synthesis: Employed as a starting material or auxiliary in the preparation of enantiomerically pure compounds.
• Agrochemical Development: Potential intermediate in the research and synthesis of specialized agrochemicals.
• Cosmetic Peptides: Can be used in the research and development of synthetic peptides for cosmetic applications.

Basic Information

Product Name	D-Aspartic Acid Dimethyl Ester Hydrochloride
CAS No.	69630-50-8
Molecular Formula	C6H11NO4 • HCl
Molecular Weight	197.62 g/mol (Free base: 161.16 g/mol)
Synonyms	D-Aspartic acid dimethyl ester HCl; (R)-2-Amino-butanedioic acid dimethyl ester hydrochloride; Dimethyl D-aspartate hydrochloride; H-D-Asp(OMe)-OMe • HCl; (R)-Dimethyl 2-aminosuccinate hydrochloride; D-Aspartic acid β-methyl ester α-methyl ester hydrochloride; Methyl (2R)-2-amino-4-methoxy-4-oxobutanoate hydrochloride
EINECS	Contact for details

Quality Control

Our D-Aspartic Acid Dimethyl Ester Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and chiral integrity, meeting the stringent requirements for pharmaceutical intermediates. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (enantiomeric excess), and impurity profiles is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). Keep the container tightly sealed in a dry environment to prevent degradation from moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.