Description

1,2-Dihydro-1'-Methylspiro[3H-Indole-3,4'-Piperidine] is a high-purity, advanced pharmaceutical intermediate characterized by its unique spirocyclic structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of complex bioactive molecules. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of central nervous system (CNS) therapeutics and other specialized active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, particularly those targeting neurological pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for the discovery of new therapeutic agents.
• CNS Drug Development: Serves as a core scaffold for compounds being investigated for potential applications in treating CNS disorders.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Reference Standard: Can be utilized as an analytical standard for quality control and method validation in API manufacturing.

Basic Information

Product Name	1,2-Dihydro-1'-Methylspiro[3H-Indole-3,4'-Piperidine]
CAS No.	69584-91-4
Molecular Formula	C14H18N2
Molecular Weight	214.31 g/mol
Synonyms	1'-Methylspiro[3H-indole-3,4'-piperidine]; 1,2-Dihydro-1'-methylspiro[3H-indole-3,4'-piperidine]; Spiro[indole-3,4'-piperidine], 1,2-dihydro-1'-methyl-; 1'-Methyl-1,2-dihydrospiro[indole-3,4'-piperidine]; 69584-91-4; 1'-Methylspiro[indole-3,4'-piperidine]; Spiro[3H-indole-3,4'-piperidine], 1,2-dihydro-1'-methyl-
EINECS	Contact for details

Quality Control

Our 1,2-Dihydro-1'-Methylspiro[3H-Indole-3,4'-Piperidine] is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D and process chemistry. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.