Description

2,4,6-Trichloronicotinic Acid is a halogenated derivative of nicotinic acid, serving as a versatile and high-value synthetic intermediate in advanced organic chemistry. Its core value proposition lies in its unique substitution pattern, which makes it a critical building block for constructing complex heterocyclic systems and active pharmaceutical ingredients (APIs). This compound is essential for research and development chemists, process engineers, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel compounds with specific biological or material properties.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Ligand and Catalyst Development: Used to create complex chelating ligands for metal catalysts in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Intermediate for synthesizing functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Serves as a scaffold for creating molecular probes to study enzyme function and biological pathways.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Product Name	2,4,6-Trichloronicotinic Acid
CAS No.	69422-72-6
Molecular Formula	C6H2Cl3NO2
Molecular Weight	226.44 g/mol
Synonyms	2,4,6-Trichloropyridine-3-carboxylic Acid; Nicotinic Acid, 2,4,6-trichloro-; 3-Pyridinecarboxylic acid, 2,4,6-trichloro-; 2,4,6-Trichloro-3-pyridinecarboxylic acid; 2,4,6-Trichloronicotinate; 69422-72-6 (CAS); Trichloronicotinic Acid
EINECS	Contact for details

Quality Control

Our 2,4,6-Trichloronicotinic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Custom purity grades, including research and GMP grades, are available to suit specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its acidic nature, keep away from incompatible materials such as strong bases and oxidizing agents. For long-term storage, consider using desiccants to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.