Description

n-Benzylcinchonidinium Chloride is a quaternary ammonium salt derived from the cinchona alkaloid cinchonidine, serving as a versatile chiral phase-transfer catalyst (PTC). Its primary value lies in enabling highly enantioselective synthetic transformations under mild conditions, which is critical for producing optically active intermediates. This compound is essential for research and development chemists in the pharmaceutical and fine chemical industries, particularly for the asymmetric synthesis of amino acids, pharmaceutical active ingredients, and other high-value chiral molecules.

Application

• As a chiral phase-transfer catalyst for the asymmetric alkylation of glycine imines.
• Enantioselective synthesis of α-amino acids and their derivatives for pharmaceutical applications.
• Catalyst in the asymmetric Michael addition and other carbon-carbon bond-forming reactions.
• Key reagent in the preparation of chiral intermediates for active pharmaceutical ingredients (APIs).
• Use in academic and industrial research for developing new asymmetric synthetic methodologies.
• Potential application in the synthesis of specialty chemicals and agrochemicals requiring high enantiomeric purity.

Basic Information

Product Name	n-Benzylcinchonidinium Chloride
CAS No.	69257-04-1
Molecular Formula	C27H31ClN2O
Molecular Weight	434.99 g/mol
Synonyms	Benzylcinchonidinium Chloride; N-Benzylcinchonidinium Chloride; Cinchonidine, N-benzyl-, chloride (1:1); (8α,9R)-N-Benzylcinchonidinium Chloride; 1-Benzylcinchonidinium Chloride; PTC Catalyst Bn-Cinchonidinium Chloride; Chiral Phase-Transfer Catalyst
EINECS	Contact for details

Quality Control

Our n-Benzylcinchonidinium Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, chiral purity, and impurity profiles. We adhere to current Good Manufacturing Practices (cGMP) where applicable, and our quality systems are designed to meet the stringent requirements of pharmaceutical R&D and fine chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.