Description

1,1'-Biphenyl, 4-Bromo-4'-(Trifluoromethyl)- is a high-value, multi-functional biphenyl derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromo and trifluoromethyl substituents, makes it an essential intermediate for creating complex molecules with tailored electronic and steric properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for constructing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring biphenyl cores with halogen and fluorine substituents for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group often contributes to improved lipophilicity and biological activity.
• Liquid Crystal & OLED Materials: Serves as a core unit in the production of advanced electronic materials, including liquid crystals for displays and organic light-emitting diodes (OLEDs), due to its rigid biphenyl structure and modifiable functional groups.
• Ligand & Catalyst Development: Employed in organometallic chemistry to create sophisticated phosphine or nitrogen-based ligands for asymmetric catalysis and cross-coupling reactions.
• Polymer & Specialty Chemical Modifier: Acts as a monomer or additive to introduce fluorine and bromine functionalities into polymers, enhancing properties like chemical resistance, thermal stability, and flame retardancy.
• Research & Development: A versatile scaffold in academic and industrial R&D for exploring new chemical spaces, structure-activity relationships (SAR), and novel synthetic methodologies.

Basic Information

Item	Details
Product Name	1,1'-Biphenyl, 4-Bromo-4'-(Trifluoromethyl)-
CAS No.	69231-87-4
Molecular Formula	C13H8BrF3
Molecular Weight	301.11 g/mol
Synonyms	4-Bromo-4'-(trifluoromethyl)biphenyl; 4'-Bromo-4-(trifluoromethyl)biphenyl; [1,1'-Biphenyl]-4-bromo-4'-(trifluoromethyl); 4-Bromo-α,α,α-trifluoro-p-terphenyl; p-Bromo-p'-(trifluoromethyl)biphenyl; 4-Bromo-4'-trifluoromethyl-1,1'-biphenyl; 4-Bromo-4'-(trifluoromethyl)-1,1'-biphenyl; 4-Bromo-4'-trifluoromethylbiphenyl
EINECS	Contact for details

Quality Control

Our production of 1,1'-Biphenyl, 4-Bromo-4'-(Trifluoromethyl)- adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure high purity and consistent lot-to-lot performance. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles. We support cGMP and ISO 9001 compliant manufacturing for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound may be sensitive to strong bases and fluorides; keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.