Description

1'-Methylspiro[Indoline-3,2'-Pyrrolidin]-2-One CAS NO 69226-42-2 is a complex spirocyclic organic compound featuring a fused indoline and pyrrolidinone structure. This heterocyclic scaffold is of significant interest in advanced pharmaceutical research and development, particularly as a versatile synthetic intermediate. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel molecular architectures with potential biological activity.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and library synthesis for high-throughput screening.
• Agrochemical Development: Acts as a precursor in the research and synthesis of new active ingredients for crop protection.
• Chemical Biology Probes: Employed in the development of molecular probes to study biological pathways and protein interactions.
• Fine Chemical Synthesis: Utilized in custom and contract synthesis for producing specialized, high-value compounds.
• Academic Research: Used in universities and research institutes for methodological development in organic and heterocyclic chemistry.

Basic Information

Product Name	1'-Methylspiro[Indoline-3,2'-Pyrrolidin]-2-One
CAS No.	69226-42-2
Molecular Formula	C13H16N2O
Molecular Weight	216.28 g/mol
Synonyms	1'-Methylspiro[indoline-3,2'-pyrrolidin]-2-one; 2H-Spiro[indole-3,2'-pyrrolidin]-2-one, 1'-methyl-; 1'-Methyl-2H-spiro[indole-3,2'-pyrrolidin]-2-one; 1'-Methylspiro[indoline-3,2'-pyrrolidin]-2-one; 69226-42-2; Spiro[indoline-3,2'-pyrrolidin]-2-one, 1'-methyl-; 1'-Methyl-1,3-dihydrospiro[indole-2,2'-pyrrolidin]-3-one
EINECS	Contact for details

Quality Control

Our 1'-Methylspiro[Indoline-3,2'-Pyrrolidin]-2-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all relevant specifications. We support cGMP standards for advanced intermediate production, ensuring reliability for critical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.