Description

n-Benzylcinchoninium Chloride is a high-purity, organocatalytic quaternary ammonium salt derived from the cinchona alkaloid family. This compound serves as a powerful and versatile chiral phase-transfer catalyst, enabling highly enantioselective synthetic transformations critical for producing optically active intermediates. It is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries who require efficient asymmetric synthesis protocols.

Application

• Asymmetric Alkylation Reactions: A key catalyst for the enantioselective alkylation of glycine imines and other pro-nucleophiles under phase-transfer conditions.
• Pharmaceutical Intermediate Synthesis: Used in the production of chiral active pharmaceutical ingredients (APIs) and complex drug candidates.
• Fine Chemical Manufacturing: Facilitates the synthesis of enantiomerically pure flavors, fragrances, and specialty chemicals.
• Agrochemical Research: Applied in the development of chiral herbicides, fungicides, and plant growth regulators.
• Academic & Process Chemistry: A valuable tool for methodological development in asymmetric catalysis and scale-up process optimization.
• Michael Additions & Conjugate Additions: Catalyzes enantioselective C-C bond-forming reactions with high stereocontrol.

Basic Information

Product Name	n-Benzylcinchoninium Chloride
CAS No.	69221-14-3
Molecular Formula	C₂₆H₃₁ClN₂O
Molecular Weight	422.99 g/mol
Synonyms	Benzylcinchoninium Chloride; N-Benzylcinchoninium Chloride; Cinchoninium, 1-benzyl-, chloride (1:1); (8α,9R)-1-Benzylcinchoninium Chloride; 1-Benzylcinchoninium Chloride; N-Benzylcinchona Bromide Analog (Chloride Salt); PTC Catalyst Bn-Cinchona-Cl
EINECS	Contact for details

Quality Control

Our n-Benzylcinchoninium Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for catalytic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and specific performance criteria.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.