Description

1-Chloro-3-o-Trityl-2-Propanol is a specialized organic intermediate featuring a trityl-protected alcohol group and a reactive chloroalkyl chain. This compound is valued for its role as a key building block in sophisticated organic synthesis, particularly in the pharmaceutical and fine chemical industries. It is primarily sought after by R&D chemists and process development teams for constructing complex molecular architectures, such as nucleoside analogs and other active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of nucleoside analogs and other antiviral or anticancer drug candidates.
• Fine Chemical Synthesis: Used as a protected synthon for introducing functionalized propanol segments into complex organic molecules.
• Protecting Group Chemistry: The o-trityl group serves as a robust protecting group for alcohols in multi-step synthetic sequences.
• Research & Development: Employed in academic and industrial R&D labs for method development and exploring new chemical entities.
• Peptide Modification: Potential use in the modification of peptides or other biomolecules to alter their properties or introduce labels.
• Material Science: Can serve as a monomer or functionalization agent in the development of specialized polymers.

Basic Information

Product Name	1-Chloro-3-o-Trityl-2-Propanol
CAS No.	69161-74-6
Molecular Formula	C22H21ClO
Molecular Weight	336.85 g/mol
Synonyms	1-Chloro-3-(triphenylmethoxy)-2-propanol; 3-(Chloro)-1-(triphenylmethoxy)-2-propanol; 2-Propanol, 1-chloro-3-(triphenylmethoxy)-; o-Trityl-glycidol chlorohydrin; (2-Hydroxy-3-chloropropyl)triphenylmethyl ether; Triphenylmethyl 2-hydroxy-3-chloropropyl ether; Glycidyl Trityl Ether Chlorohydrin
EINECS	Contact for details

Quality Control

Our 1-Chloro-3-o-Trityl-2-Propanol is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.