Description

1H-Pyrrole-2-Carboxylic Acid, 4-Ethynyl- (9Ci) is a specialized heterocyclic building block featuring both a carboxylic acid and an ethynyl (acetylene) functional group on a pyrrole core. This unique bifunctional structure makes it a valuable intermediate for the synthesis of complex molecules in advanced research and development. It is primarily sought by pharmaceutical, agrochemical, and materials science industries for applications in medicinal chemistry, polymer synthesis, and the development of novel functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in the development of kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides with specific modes of action.
• Material Science & Polymer Chemistry: Serves as a monomer or cross-linking agent for creating conductive polymers, specialty coatings, and advanced organic frameworks.
• Chemical Research & Development: A versatile reagent for organic synthesis, enabling click chemistry via its alkyne group and further derivatization through its acid functionality.
• Ligand & Catalyst Development: Used to create novel ligands for metal complexes and catalysts used in asymmetric synthesis.

Basic Information

Product Name	1H-Pyrrole-2-Carboxylic Acid, 4-Ethynyl- (9Ci)
CAS No.	69151-83-3
Molecular Formula	C7H5NO2
Molecular Weight	135.12 g/mol
Synonyms	4-Ethynyl-1H-pyrrole-2-carboxylic acid; 4-Ethynylpyrrole-2-carboxylic acid; 4-Ethynyl-2-pyrrolecarboxylic acid; 2-Carboxy-4-ethynylpyrrole; 4-Ethynyl-1H-pyrrole-2-carboxylic acid (9CI); 4-Ethynyl-2-carboxypyrrole; 69151-83-3 (CAS)
EINECS	Contact for details

Quality Control

Our production of 1H-Pyrrole-2-Carboxylic Acid, 4-Ethynyl- adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for your critical syntheses. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.