Description

2-Oxo-2-[[4-(Trifluoromethyl)Phenyl]Amino]Acetic Acid is a high-purity organic intermediate featuring a reactive oxo-acetic acid moiety linked to a trifluoromethyl-substituted aniline. This compound is valued for its role as a versatile building block in advanced synthesis, particularly where the introduction of the trifluoromethyl group is desired to modulate the physicochemical properties of target molecules. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially protease inhibitors and other small molecule therapeutics where the CF₃ group enhances metabolic stability and lipophilicity.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the bioactivity often imparted by the trifluoromethylphenyl moiety.
• Material Science Research: Serves as a monomer or functionalization agent in the development of specialty polymers and advanced organic materials with tailored surface properties.
• Chemical Biology & Proteomics: Employed as a scaffold or labeling reagent in the design of activity-based probes and enzyme inhibitors for biochemical research.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom chemical synthesis services catering to the needs of R&D departments across multiple industries.

Basic Information

Product Name	2-Oxo-2-[[4-(Trifluoromethyl)Phenyl]Amino]Acetic Acid
CAS No.	69066-42-8
Molecular Formula	C₁₀H₆F₃NO₃
Molecular Weight	245.16 g/mol
Synonyms	N-(4-Trifluoromethylphenyl)oxamic Acid; 2-Oxo-2-[(4-trifluoromethylphenyl)amino]acetic Acid; 4-(Trifluoromethyl)phenyloxamic Acid; Oxamic Acid, N-[4-(trifluoromethyl)phenyl]-; α-Oxo-N-[4-(trifluoromethyl)phenyl]glycine; 69066-42-8; (4-Trifluoromethylphenyl)oxamic Acid
EINECS	Contact for details

Quality Control

Every batch of 2-Oxo-2-[[4-(Trifluoromethyl)Phenyl]Amino]Acetic Acid is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing, including chromatographic purity analysis and identity confirmation, to ensure compliance with exacting industry standards. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.