Description

2-(Piperazin-1-Yl)Quinoline Hydrochloride is a high-purity pharmaceutical intermediate and research chemical of significant synthetic utility. Its core value lies in its role as a versatile building block for the development of novel bioactive compounds, particularly in medicinal chemistry. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and life science industries engaged in drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, and oncology.
• Medicinal Chemistry Research: Serves as a critical scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs) with optimized biological activity.
• Ligand Synthesis: Used in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs) due to the chelating properties of the piperazine-quinoline structure.
• Agrochemical Development: Employed in the research and synthesis of novel crop protection agents and pesticides.
• Biochemical Tool Compound: Utilized in academic and industrial research laboratories as a standard or probe molecule for various biochemical assays.

Basic Information

Product Name	2-(Piperazin-1-Yl)Quinoline Hydrochloride
CAS No.	68942-28-9
Molecular Formula	C13H16N3·HCl
Molecular Weight	249.75 g/mol
Synonyms	2-(1-Piperazinyl)quinoline hydrochloride; Quinoline, 2-(1-piperazinyl)-, hydrochloride; 2-Piperazinylquinoline hydrochloride; 1-(Quinolin-2-yl)piperazine hydrochloride; 2-Quinolylpiperazine hydrochloride; 68942-28-9; UNII-9Q7J8Z4K1P
EINECS	Contact for details

Quality Control

Our 2-(Piperazin-1-Yl)Quinoline Hydrochloride is manufactured under strict quality control protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation via IR and NMR spectroscopy, and tests for residual solvents and heavy metals. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure full traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.