Description

4-Bromo-2-Methylbenzoic Acid is a versatile halogenated benzoic acid derivative that serves as a critical building block in advanced organic synthesis. Its value lies in the strategic positioning of the bromine and methyl substituents, which enable selective functionalization for creating complex molecular architectures. This compound is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and material science industries who require high-purity intermediates for developing active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, where the bromine atom acts as a handle for further cross-coupling reactions.
• Liquid Crystal & OLED Materials: Serves as a building block for synthesizing functionalized aromatic cores essential in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer Chemistry: Incorporated as a monomer or chain modifier to introduce aromaticity and bromine functionality into specialty polymers, enhancing thermal stability and flame retardancy.
• Organic Synthesis & Catalysis: Employed in Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to construct biaryl systems common in many high-value compounds.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D labs exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	4-Bromo-2-Methylbenzoic Acid
CAS No.	68837-59-2
Molecular Formula	C8H7BrO2
Molecular Weight	215.04 g/mol
Synonyms	2-Methyl-4-bromobenzoic Acid; 4-Bromo-o-toluic Acid; 4-Bromo-2-methylbenzenecarboxylic Acid; Benzoic acid, 4-bromo-2-methyl-; 4-Bromo-2-toluic Acid; 4-Bromo-2-methyl-benzoic acid; 2-Methyl-4-bromo-benzoic acid
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Methylbenzoic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices. Our commitment to traceability and documentation supports our clients' needs for regulatory filings in cGMP environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	158 - 162 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.