Description

(R)-5,6,6A,7-Tetrahydro-1,2,9,10-Tetramethoxy-6-Methyl-4H-Dibenzo[De,G]Quinolinium Bromide is a high-purity, chiral alkaloid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical pharmacological reference standard and a versatile chemical building block for synthesizing novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in neuroscience, receptor studies, and the development of new chemical entities.

Application

• Pharmaceutical Reference Standard: Used for method development, validation, and quality control in analytical laboratories.
• Neuroscience Research: Acts as a key intermediate or ligand in the study of neurological receptors and signal transduction pathways.
• Medicinal Chemistry: Serves as a sophisticated chiral scaffold for the synthesis of potential drug candidates targeting specific biological activities.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of complex alkaloid-based molecules.
• Academic Research: Used in universities and institutes for studying the structure-activity relationships (SAR) of tetrahydroisoquinoline derivatives.

Basic Information

Product Name	(R)-5,6,6A,7-Tetrahydro-1,2,9,10-Tetramethoxy-6-Methyl-4H-Dibenzo[De,G]Quinolinium Bromide
CAS No.	68742-86-9
Molecular Formula	C22H28NO4•Br
Molecular Weight	450.37 g/mol
Synonyms	(R)-Tetrahydropalmatine Quaternary Salt; (R)-THP Bromide; (R)-Canadine Methodide Derivative; (R)-5,6,6a,7-Tetrahydro-1,2,9,10-tetramethoxy-6-methyl-4H-dibenzo[de,g]quinolinium bromide; (R)-Stylopine Quaternary Ammonium Salt; (R)-Corydaline Quaternary Salt; (R)-Tetrahydroberberine Quaternary Salt
EINECS	Contact for details

Quality Control

Our (R)-5,6,6A,7-Tetrahydro-1,2,9,10-Tetramethoxy-6-Methyl-4H-Dibenzo[De,G]Quinolinium Bromide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for chiral purity and assay, to ensure it meets the stringent requirements for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. Handle and store in accordance with good laboratory practices.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (R-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.