Description

(3Ar,4R,6E,9S,10Z,11Ar)-9-Acetoxy-3A,4,5,8,9,11A-Hexahydro-4-Hydroxy-6,10-Dimethyl-3-Methylenecyclodeca[B]Furan-2(3H)-One is a complex sesquiterpene lactone derivative, a class of compounds renowned for their significant biological activity. This high-purity chemical building block is critical for advanced pharmaceutical research and development, particularly in the synthesis of novel therapeutic agents. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical industries for its unique structural framework.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially in anti-inflammatory and anticancer drug discovery programs.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to explore and optimize biological activity profiles.
• Natural Product Synthesis: Acts as a sophisticated intermediate in the total or semi-synthesis of complex natural products and their analogues.
• Biochemical Tool Compound: Employed in biochemical assays to study specific biological pathways and enzyme interactions due to its potential modulator activity.
• Agrochemical Research: Investigated as a precursor for developing new crop protection agents with novel modes of action.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	(3Ar,4R,6E,9S,10Z,11Ar)-9-Acetoxy-3A,4,5,8,9,11A-Hexahydro-4-Hydroxy-6,10-Dimethyl-3-Methylenecyclodeca[B]Furan-2(3H)-One
CAS No.	68628-57-9
Molecular Formula	C17H22O5
Molecular Weight	306.36 g/mol
Synonyms	9-Acetoxy-4-hydroxy-6,10-dimethyl-3-methylidene-4,5,8,9,11a,3a-hexahydrocyclodeca[b]furan-2(3H)-one; (3aR,4R,6E,9S,10Z,11aR)-9-Acetoxy-4-hydroxy-6,10-dimethyl-3-methylidene-3a,4,5,8,9,11a-hexahydrocyclodeca[b]furan-2(3H)-one; A sesquiterpene lactone acetate derivative; Cyclodeca[b]furan-2(3H)-one derivative; Contact for additional trade names and abbreviations.
EINECS	Contact for details

Quality Control

Our (3Ar,4R,6E,9S,10Z,11Ar)-9-Acetoxy-3A,4,5,8,9,11A-Hexahydro-4-Hydroxy-6,10-Dimethyl-3-Methylenecyclodeca[B]Furan-2(3H)-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and structural confirmation via NMR and MS, to ensure it meets exacting research-grade specifications. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. This compound may be light-sensitive and moisture-sensitive; prolonged exposure to heat, light, or humidity should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Chiral Purity	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.