Description

4,5,6-Trifluoro-1-Methyl-1H-Benzo[De]Quinoline-2,3-Dicarboxylic Acid Dimethyl Ester is a high-purity, multifunctional fluorinated heterocyclic building block. This compound is valued for its unique molecular architecture, which combines a fused quinoline core with strategically placed fluorine atoms and ester functionalities, making it an essential intermediate for advanced material and pharmaceutical synthesis. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and organic electronics industries for constructing complex molecules with tailored properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Research: Used in the synthesis of advanced herbicides, fungicides, and pesticides, where the fluorine atoms enhance biological activity, metabolic stability, and lipophilicity.
• Organic Light-Emitting Diodes (OLEDs): Serves as a precursor for electron-transport materials (ETMs) or host materials in OLED displays and lighting due to its rigid, planar structure and fluorinated electron-deficient character.
• Ligand Synthesis: Utilized in organometallic chemistry to create sophisticated chelating ligands for catalysis, leveraging the nitrogen and oxygen donor atoms.
• Fluorescent Dye & Sensor Development: Acts as a core structure for creating new fluorophores and chemosensors used in bio-imaging and diagnostic applications.
• Polymer & Material Science: Incorporated into specialty polymers to impart high thermal stability, chemical resistance, and specific optical or electronic properties.

Basic Information

Product Name	4,5,6-Trifluoro-1-Methyl-1H-Benzo[De]Quinoline-2,3-Dicarboxylic Acid Dimethyl Ester
CAS No.	68464-45-9
Molecular Formula	C₁₈H₁₂F₃NO₄
Molecular Weight	363.29 g/mol
Synonyms	1-Methyl-4,5,6-trifluorobenzo[de]quinoline-2,3-dicarboxylic acid dimethyl ester; Dimethyl 1-methyl-4,5,6-trifluorobenzo[de]quinoline-2,3-dicarboxylate; 4,5,6-Trifluoro-1-methyl-1H-benzo[de]quinoline-2,3-dicarboxylic acid dimethyl ester; 1H-Benzo[de]quinoline-2,3-dicarboxylic acid, 4,5,6-trifluoro-1-methyl-, dimethyl ester; 68464-45-9; TFMBQ-DM; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 4,5,6-Trifluoro-1-Methyl-1H-Benzo[De]Quinoline-2,3-Dicarboxylic Acid Dimethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.