Description

[1R-(1Alpha,3Alpha,4Aalpha)]-2,3,4,4A,5,6-Hexahydro-2,2-Dimethyl-1,3-Methanonaphthalen-7(1H)-One is a high-purity, complex bicyclic ketone that serves as a critical chiral building block and synthetic intermediate in advanced organic synthesis. Its unique, rigid molecular framework is essential for constructing complex molecules with precise stereochemistry. This compound is primarily sought after by research and development laboratories in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the creation of advanced, stereospecific pesticides and herbicides where the specific spatial orientation of the molecule is crucial for bioactivity.
• Asymmetric Catalysis Research: Serves as a sophisticated ligand precursor or a test substrate in the development of new chiral catalysts and methodologies.
• Fragrance & Flavor Chemistry: Acts as a starting material for synthesizing complex, musky, or woody odorant molecules due to its decalin-related structure.
• Material Science Research: Investigated as a monomer or cross-linking agent for creating polymers with specific thermal and mechanical properties.
• Academic & Institutional Research: Utilized in organic chemistry departments and R&D facilities for methodological studies and training in complex molecule synthesis.

Basic Information

Item	Details
Product Name	[1R-(1Alpha,3Alpha,4Aalpha)]-2,3,4,4A,5,6-Hexahydro-2,2-Dimethyl-1,3-Methanonaphthalen-7(1H)-One
CAS No.	68433-81-8
Molecular Formula	C₁₃H₁₈O
Molecular Weight	190.28 g/mol
Synonyms	(1R,3R,4aS)-2,2-Dimethyl-1,3,4,4a,5,6-hexahydro-1,3-methanonaphthalen-7(2H)-one; (1R,3R,4aS)-2,2-Dimethyl-3,4,4a,5,6,7-hexahydro-1H-1,3-methanonaphthalen-7-one; (+)-2,2-Dimethyl-1,3,4,4a,5,6-hexahydro-1,3-methanonaphthalen-7(2H)-one; (1R,3R,4aS)-Decahydro-2,2-dimethyl-1,3-methanonaphthalen-7-one; Bicyclo[2.2.2]octane derivative; Chiral decalin ketone
EINECS	Contact for details

Quality Control

Our [1R-(1Alpha,3Alpha,4Aalpha)]-2,3,4,4A,5,6-Hexahydro-2,2-Dimethyl-1,3-Methanonaphthalen-7(1H)-One is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure high chemical and isomeric purity suitable for demanding synthetic applications. A detailed Certificate of Analysis (COA) with full chromatographic data is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.