Description

(E)-2-(4-Chlorophenylsulfonyl)-3-Hydrazinylacrylonitrile is a versatile and high-value synthetic intermediate characterized by its unique sulfonyl hydrazone-acrylonitrile hybrid structure. This compound is critical for advanced organic synthesis, particularly in the construction of complex nitrogen- and sulfur-containing heterocycles. It is primarily sought after by research institutions and pharmaceutical development companies engaged in medicinal chemistry and agrochemical discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key building block for synthesizing novel drug candidates, particularly those targeting enzymes or receptors where the sulfonyl and hydrazinyl groups are pharmacologically active.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its potential bioactivity as a precursor for active ingredients.
• Heterocyclic Chemistry: An essential precursor for the synthesis of complex heterocyclic scaffolds such as pyrazoles, triazoles, and other fused ring systems important in material and life sciences.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and inhibitors for studying biological pathways and protein functions.
• Material Science Research: Investigated as a monomer or cross-linking agent for creating specialized polymers with unique thermal or chemical properties.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in client-specific, multi-step synthetic routes.

Basic Information

Product Name	(E)-2-(4-Chlorophenylsulfonyl)-3-Hydrazinylacrylonitrile
CAS No.	68342-62-1
Molecular Formula	C9H8ClN3O2S
Molecular Weight	257.69 g/mol
Synonyms	2-[(E)-[(4-Chlorophenyl)sulfonyl]methylidene]hydrazinylideneacetonitrile; 3-Hydrazinyl-2-[(4-chlorophenyl)sulfonyl]acrylonitrile; (E)-3-Hydrazinyl-2-((4-chlorophenyl)sulfonyl)acrylonitrile; 2-((4-Chlorophenyl)sulfonyl)-3-hydrazinylacrylonitrile; Acrylonitrile, 2-[(4-chlorophenyl)sulfonyl]-3-hydrazinyl-, (E)-; 4-Chloro-α-(cyanoethylidene)benzenesulfonohydrazide
EINECS	Contact for details

Quality Control

Our (E)-2-(4-Chlorophenylsulfonyl)-3-Hydrazinylacrylonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.