Description

Edaravone is a potent synthetic antioxidant compound with significant neuroprotective properties. Its primary commercial value lies in its critical role as the active pharmaceutical ingredient (API) in treatments for acute ischemic stroke and amyotrophic lateral sclerosis (ALS). This high-purity compound is essential for pharmaceutical manufacturers, research institutions, and contract development and manufacturing organizations (CDMOs) engaged in neurology-focused drug development and production.

Application

• Pharmaceutical Active Ingredient (API): Primary use in the formulation of injectable drugs for the treatment of acute ischemic stroke.
• Neurological Disease Therapy: Key component in medications for Amyotrophic Lateral Sclerosis (ALS), helping to slow disease progression.
• Neuroprotective Agent Research: Used in preclinical and clinical research to study mechanisms of oxidative stress and neuronal cell death.
• Formulation Development: Serves as a reference standard and raw material for developing new drug delivery systems, including IV solutions.
• Contract Manufacturing: Supplied to CDMOs for the production of finished dosage forms under cGMP guidelines.
• Analytical Standard: Utilized as a high-purity standard in quality control laboratories for HPLC and other chromatographic assays.

Basic Information

Product Name	Edaravone
CAS No.	68195-63-1
Molecular Formula	C10H10N2O
Molecular Weight	174.20 g/mol
Synonyms	3-Methyl-1-phenyl-2-pyrazolin-5-one; MCI-186; Radicava; 1-Phenyl-3-methyl-5-pyrazolone; 3-Methyl-1-phenyl-5-pyrazolone; 5-Pyrazolone, 3-methyl-1-phenyl-; Edaravone (USAN); Edaravonum
EINECS	Contact for details

Quality Control

Our Edaravone is manufactured under strict quality management systems to ensure it meets the stringent requirements for pharmaceutical actives. We provide material that conforms to relevant pharmacopeial standards (e.g., USP, EP) where applicable. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Loss on Drying	≤ 0.5%
Sulfated Ash	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.