Description

1-Ethyl-7-Chloro-6-Fluoro-1,4-Dihydro-4-Oxoquinoline-3-Carboxylic Acid is a high-purity pharmaceutical intermediate belonging to the quinolone carboxylic acid class. This compound is a critical building block in the synthesis of advanced fluoroquinolone antibiotics, valued for its precise molecular structure that imparts essential antibacterial properties to the final active pharmaceutical ingredient (API). It is primarily required by manufacturers in the pharmaceutical and fine chemical industries for research, development, and commercial-scale production of antimicrobial agents.

Application

• Key Intermediate for Fluoroquinolone Antibiotics: Serves as a core precursor in the synthesis of potent antibacterial agents.
• Pharmaceutical Research & Development (R&D): Used in the discovery and process development of new antimicrobial compounds.
• Active Pharmaceutical Ingredient (API) Manufacturing: Employed in the commercial-scale production of finished antibiotic drugs.
• Chemical Synthesis Studies: Utilized in academic and industrial research to explore novel quinolone derivatives and reaction pathways.
• Reference Standard: Acts as a high-purity analytical standard for quality control and regulatory testing in pharmaceutical labs.

Basic Information

Product Name	1-Ethyl-7-Chloro-6-Fluoro-1,4-Dihydro-4-Oxoquinoline-3-Carboxylic Acid
CAS No.	68077-26-9
Molecular Formula	C₁₂H₉ClFNO₃
Molecular Weight	269.66 g/mol
Synonyms	7-Chloro-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid; 1-Ethyl-7-chloro-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 68077-26-9; Quinolone-3-carboxylic acid derivative; Fluoroquinolone intermediate; 7-Chloro-6-fluoro-1-ethyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-Ethyl-7-Chloro-6-Fluoro-1,4-Dihydro-4-Oxoquinoline-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability, consistency, and compliance with your R&D or cGMP production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.