Description

Bis-Boc-Spermidine is a protected derivative of the naturally occurring polyamine spermidine, featuring two tert-butoxycarbonyl (Boc) protecting groups. This compound is a critical building block in organic synthesis and pharmaceutical research, enabling the controlled introduction of the spermidine moiety into complex molecules. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors for developing novel therapeutics and biochemical probes.

Application

• Pharmaceutical Intermediate: Key synthetic precursor for the development of polyamine-based drugs and enzyme inhibitors.
• Bioconjugation & Probe Synthesis: Used to create labeled spermidine derivatives for cellular uptake, trafficking, and biochemical mechanism studies.
• Peptide & Protein Modification: Serves as a linker or modifier to introduce polyamine chains, altering the physicochemical properties of biomolecules.
• Organic Synthesis Building Block: Essential for the multi-step synthesis of complex natural products and macrocyclic compounds requiring protected polyamine structures.
• Biochemical Research: Employed in studies of polyamine metabolism, autophagy, and cell signaling pathways.
• Material Science: Potential use in creating functionalized polymers and surfaces with amine-rich properties.

Basic Information

Product Name	Bis-Boc-Spermidine
CAS No.	68076-39-1
Molecular Formula	C19H38N4O4
Molecular Weight	386.53 g/mol
Synonyms	N1,N8-Bis(tert-butoxycarbonyl)spermidine; N1,N8-Di-Boc-spermidine; 1,8-Bis-Boc-spermidine; Spermidine, N,N'-bis(1,1-dimethylethoxy)carbonyl]-; Spermidine, N,N'-bis[(1,1-dimethylethoxy)carbonyl]-; N1,N8-Di-(tert-butoxycarbonyl)spermidine; Bis(tert-butoxycarbonyl)spermidine; Spermidine Bis-Boc Derivative
EINECS	Contact for details

Quality Control

Our Bis-Boc-Spermidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (NMR, IR), to ensure it meets the stringent requirements for research and development. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation or storage under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.