Description

10-Azabenzo(A)Pyrene 4,5-Oxide is a high-purity, specialized heterocyclic aromatic compound of significant interest in advanced chemical research and development. This compound serves as a critical reference standard and synthetic intermediate for studying metabolic pathways and mutagenic activity related to polycyclic aromatic hydrocarbons (PAHs). It is primarily utilized by pharmaceutical R&D laboratories, analytical testing facilities, and academic research institutions focused on toxicology, environmental science, and carcinogenesis studies.

Application

• Analytical Reference Standard: Used as a certified standard in HPLC, GC-MS, and LC-MS for the quantification and identification of PAH metabolites and related compounds in complex matrices.
• Biochemical Research: Employed in studies investigating the metabolic activation, DNA adduct formation, and mutagenic mechanisms of polycyclic aromatic compounds.
• Toxicology & Environmental Testing: Serves as a key reagent in assays designed to assess the genotoxic and carcinogenic potential of environmental pollutants and combustion by-products.
• Pharmaceutical Development: Utilized as a building block or a model compound in the synthesis and testing of novel therapeutic agents or inhibitors targeting specific enzymatic pathways.
• Academic Research: A vital tool for universities and research institutes conducting fundamental studies in organic chemistry, bioorganic chemistry, and chemical carcinogenesis.

Basic Information

Item	Detail
Product Name	10-Azabenzo(A)Pyrene 4,5-Oxide
CAS No.	67977-01-9
Molecular Formula	C19H11NO
Molecular Weight	269.30 g/mol
Synonyms	10-Azabenzo[a]pyrene 4,5-oxide; 4,5-Epoxy-4,5-dihydro-10-azabenzo[a]pyrene; 10-Aza-BaP 4,5-oxide; Benzo[a]pyridine, 4,5-epoxy-1,2,3,5,6,10b-hexahydro-; 1,2-Epoxy-1,2-dihydro-10-azabenzo[a]pyrene; 10-Aza-BAP 4,5-oxide; 10-Azabenzo(a)pyrene-4,5-oxide
EINECS	Contact for details

Quality Control

Every batch of 10-Azabenzo(A)Pyrene 4,5-Oxide is manufactured and analyzed under strict quality management protocols to ensure identity, purity, and consistency. Our products undergo rigorous quality testing using advanced analytical techniques to ensure compliance with industry standards. Comprehensive Certificates of Analysis (COA) detailing purity, assay results, and chromatographic data are available upon request to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its light-sensitive and easily oxidized nature, it is recommended to handle under an inert atmosphere for long-term storage and to minimize repeated exposure to air.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 5.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.