Description

4-o-Methyl-n-Acetylneuraminic Acid is a chemically modified derivative of N-acetylneuraminic acid, a fundamental sialic acid. This methylated analog is a critical building block and reference standard in advanced biochemical research and pharmaceutical development. It is primarily utilized by researchers and manufacturers in the life sciences sector for studying carbohydrate-protein interactions, enzyme mechanisms, and for the synthesis of more complex glycoconjugates.

Application

• Biochemical Research: Serves as a key intermediate and reference standard in the study of sialic acid metabolism, glycosylation pathways, and sialidase/sialyltransferase enzyme activities.
• Pharmaceutical Development: Used as a precursor or analog in the research and synthesis of novel glycotherapeutic agents, including antiviral and anti-inflammatory compounds.
• Glycobiology Studies: Essential for investigating cell surface recognition, cell signaling, and immune response modulation mediated by sialylated glycans.
• Diagnostic Reagent Manufacturing: Employed in the production of high-specificity reagents for detecting and quantifying sialic acid-related biomarkers.
• Academic & Industrial R&D: A vital tool for universities, research institutes, and biotech companies exploring carbohydrate chemistry and its applications in medicine.

Basic Information

Product Name	4-o-Methyl-n-Acetylneuraminic Acid
CAS No.	67974-39-4
Molecular Formula	C12H21NO9
Molecular Weight	323.30 g/mol
Synonyms	4-O-Methyl-N-acetylneuraminic acid; 4-O-Methyl-Neu5Ac; 4-O-Methyl-5-acetamido-3,5-dideoxy-D-glycero-D-galacto-non-2-ulopyranosonic acid; Methylated Sialic Acid; 4-OMe-Neu5Ac; 4-Methoxy-N-acetylneuraminic acid
EINECS	Contact for details

Quality Control

Our 4-o-Methyl-n-Acetylneuraminic Acid is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent high purity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and must be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.