Description

3-Chloro-4-Methylbenzylamine is a versatile aromatic amine building block characterized by its chloro and methyl substituents, which impart unique reactivity and steric properties. This compound is essential for the synthesis of advanced pharmaceutical intermediates, agrochemicals, and functional materials, offering a critical handle for further chemical modifications. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce a benzylamine moiety into complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, where the benzylamine group acts as a core structural element.
• Ligand and Catalyst Development: Serves as a starting material for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Polymer and Resin Modifier: Incorporated into polymer chains to enhance material properties such as adhesion, thermal stability, or chemical resistance.
• Dye and Pigment Manufacturing: Acts as an intermediate in the production of complex organic dyes and colorants.
• Cross-coupling Reactions: Utilized in palladium-catalyzed reactions like Buchwald-Hartwig amination for constructing C-N bonds.

Basic Information

Product Name	3-Chloro-4-Methylbenzylamine
CAS No.	67952-93-6
Molecular Formula	C8H10ClN
Molecular Weight	155.62 g/mol
Synonyms	(3-Chloro-4-methylphenyl)methanamine; 1-(Aminomethyl)-2-chloro-4-methylbenzene; 3-Chloro-p-tolylmethylamine; 3-Chloro-4-methylbenzenemethanamine; 2-Chloro-4-(aminomethyl)toluene; α-Amino-3-chloro-4-methyltoluene; Benzenemethanamine, 3-chloro-4-methyl-
EINECS	Contact for details

Quality Control

Our 3-Chloro-4-Methylbenzylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets exacting standards for research and industrial use. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is easily oxidized and should be handled with care to minimize exposure to air.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.