Description

6-o-(Triphenylmethyl)-D-Glucopyranose Tetraacetate is a key protected carbohydrate intermediate, specifically a fully acetylated glucose derivative with a trityl (triphenylmethyl) group at the 6-position. This compound is essential for synthetic chemists as it provides orthogonal protection for primary hydroxyl groups, enabling precise, sequential deprotection strategies in complex oligosaccharide and glycoconjugate synthesis. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, diagnostic agents, and advanced materials.

Application

• Glycosylation Reactions: Serves as a crucial glycosyl donor or acceptor building block in the stereoselective synthesis of complex oligosaccharides and glycans.
• Pharmaceutical Intermediates: Used in the research and development of carbohydrate-based drugs, including antibiotics, antivirals, and anticancer agents.
• Glycoconjugate Synthesis: A fundamental precursor for creating glycoproteins, glycolipids, and other biologically active conjugates for immunological studies.
• Chemical Biology Probes: Employed in the synthesis of labeled sugar analogs and probes for studying carbohydrate metabolism and enzyme mechanisms.
• Material Science: Acts as a monomer or starting material for synthesizing specialized polymers and dendrimers with tailored surface properties.
• Process Development: Used in scaling up synthetic routes for carbohydrate-active pharmaceutical ingredients (APIs) under Good Manufacturing Practice (GMP) conditions.

Basic Information

Item	Details
Product Name	6-o-(Triphenylmethyl)-D-Glucopyranose Tetraacetate
CAS No.	67919-36-2
Molecular Formula	C31H32O9
Molecular Weight	548.58 g/mol
Synonyms	1,2,3,4-Tetra-O-acetyl-6-O-trityl-β-D-glucopyranose; 6-O-Trityl-1,2,3,4-tetra-O-acetyl-β-D-glucopyranose; 6-O-Triphenylmethyl-1,2,3,4-tetra-O-acetyl-D-glucopyranose; β-D-Glucopyranose, 6-O-trityl-, 1,2,3,4-tetraacetate; Trityl-protected glucose tetraacetate; 6-Trityl-D-glucose tetraacetate
EINECS	Contact for details

Quality Control

Our 6-o-(Triphenylmethyl)-D-Glucopyranose Tetraacetate is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive analytical data, including HPLC purity, NMR confirmation, and optical rotation verification. A detailed Certificate of Analysis (COA) is supplied with each batch to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Specific Optical Rotation	Contact for details
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.