Description

6-o-Triphenylmethyl-D-Glucopyranose is a key protected carbohydrate intermediate, specifically a glucopyranose derivative with a trityl (triphenylmethyl) group at the 6-position. This compound is critical for synthetic chemists as it provides a robust and selectively removable protecting group for primary hydroxyl functions in complex oligosaccharide and nucleoside synthesis. It is an essential building block for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors developing advanced glycosylated compounds, antiviral agents, and novel biomaterials.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the multi-step synthesis of complex active pharmaceutical ingredients (APIs), particularly nucleoside analogues and glycoconjugates.
• Oligosaccharide Synthesis: Used as a protected glucose building block for the controlled, sequential construction of specific glycosidic linkages in target oligosaccharides and polysaccharides.
• Glycobiology Research: Enables the study of glycosylation processes and the development of glycan-based probes, inhibitors, and vaccines in academic and industrial R&D settings.
• Nucleoside Chemistry: Facilitates the synthesis of modified nucleosides and nucleotides by protecting the sugar moiety, which is vital for antiviral and anticancer drug discovery.
• Fine Chemical Production: Acts as a specialized intermediate for creating high-value chiral compounds, flavors, and fragrances that require precise stereochemical control.
• Bioconjugation: Employed in the preparation of chemically defined glycoproteins, glycolipids, and other bioconjugates for diagnostic and therapeutic applications.

Basic Information

Product Name	6-o-Triphenylmethyl-D-Glucopyranose
CAS No.	67919-34-0
Molecular Formula	C25H26O6
Molecular Weight	422.47 g/mol
Synonyms	6-O-Trityl-D-glucopyranose; 6-O-Triphenylmethyl-D-glucose; D-Glucose, 6-O-(triphenylmethyl)-; 6-O-(Triphenylmethyl)-D-glucopyranose; Trityl-β-D-glucopyranoside (anomeric mixture); 6-Trityl-D-glucose; 6-O-Trityl-1,2,3,4-tetra-O-acetyl-β-D-glucopyranose (precursor related); 6-O-(Triphenylmethyl)-α/β-D-glucopyranose
EINECS	Contact for details

Quality Control

Our 6-o-Triphenylmethyl-D-Glucopyranose is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (NMR, IR), to ensure it meets the high standards required for synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing batch-specific results for purity, residual solvents, and other critical parameters. Our quality commitment supports compliance in cGMP and research-grade supply chains.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation [α]²⁰D	Contact for details
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.