Description

Phosphoric Acid (18O4, 96%) 80-85% In Water-18O CAS NO 67863-17-6 is a high-purity, isotopically labeled derivative of phosphoric acid, where the oxygen atoms are enriched with the stable isotope Oxygen-18 (18O). This specialized grade is critical for applications requiring precise molecular tracing and analysis, offering a distinct advantage in research and development. It is an essential reagent for scientists and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require labeled compounds for metabolic studies, reaction mechanism elucidation, and analytical method development.

Application

• Metabolic Pathway Tracing: Used as a labeled precursor in in vivo and in vitro studies to track phosphate and phosphorylated compound metabolism in biological systems.
• NMR Spectroscopy: Serves as a valuable probe in Nuclear Magnetic Resonance (NMR) studies, particularly in 31P NMR, due to the 18O isotope's effect on chemical shifts and coupling constants.
• Mass Spectrometry Standards: Employed as an internal standard or reference compound in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) for accurate quantification.
• Reaction Mechanism Studies: Utilized in chemical synthesis and catalysis research to investigate reaction pathways involving phosphate transfer or hydrolysis.
• Pharmaceutical Research: Integral in the development and testing of phosphate-based drugs, enabling detailed pharmacokinetic and biodistribution studies.
• Geochemical & Environmental Tracing: Applied in studies of phosphate cycling in ecosystems, soil science, and oceanography to understand source and sink processes.

Basic Information

Item	Detail
Product Name	Phosphoric Acid (18O4, 96%) 80-85% In Water-18O
CAS No.	67863-17-6
Molecular Formula	H318O4P
Molecular Weight	101.00 g/mol (approximate, based on 18O enrichment)
Synonyms	Orthophosphoric Acid-18O4; Phosphoric-18O4 Acid; [18O4]Phosphoric Acid; 18O-Labeled Phosphoric Acid; H3PO4-18O4; Isotopically Labeled Phosphoric Acid; Phosphoric Acid (18O Labeled); Tetraoxophosphoric Acid-18O4
EINECS	Contact for details

Quality Control

Every batch of our Phosphoric Acid (18O4) is produced and analyzed under stringent conditions to ensure isotopic and chemical purity. We provide comprehensive Certificates of Analysis (COA) that detail key parameters including isotopic enrichment (Atom % 18O), chemical assay, and impurity profiles. Our quality systems are designed to meet the exacting requirements of advanced research and regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Due to its nature as a strong acid, ensure containers are made of compatible materials (e.g., fluoropolymer) and are clearly labeled. Keep away from incompatible materials such as strong bases and reactive metals.

Specification

Item	Specification
Appearance	Colorless to slightly yellow viscous liquid
Identification (IR/NMR)	Conforms to structure
Isotopic Enrichment (Atom % 18O)	≥ 96%
Concentration (in H218O)	80 - 85% w/w
Assay (Titration)	≥ 98.0%
Chemical Purity (HPLC)	≥ 99.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.