Description

Anion Standard - Citrate CAS NO 126-44-3 is a high-purity analytical reference material, specifically formulated for the precise calibration and validation of instruments in ion chromatography and related analytical techniques. This standard is critical for ensuring accurate quantification of citrate anions in complex sample matrices, directly addressing the need for reliable quality control and method development. It is an essential tool for analytical laboratories in the pharmaceutical, food & beverage, environmental monitoring, and biotechnology industries where precise anion analysis is paramount.

Application

• Primary Standard for Ion Chromatography (IC): Used for the calibration of IC systems to ensure accurate measurement of citrate concentrations in samples.
• Method Development and Validation: Serves as a critical reference compound for developing, optimizing, and validating new analytical methods for anion detection.
• Quality Control in Pharmaceuticals: Employed to verify citrate levels in drug formulations, buffers, and parenteral nutrition solutions where citrate is used as an anticoagulant or stabilizer.
• Food and Beverage Analysis: Used to quantify citrate, a common acidulant and preservative, in soft drinks, juices, dairy products, and processed foods for compliance and labeling.
• Environmental and Water Testing: Applied in the analysis of water samples to monitor citrate levels, which can be an indicator of industrial discharge or biological activity.
• Clinical and Diagnostic Testing: Utilized in clinical assays to measure citrate in biological fluids like urine and plasma for metabolic studies.
• Biotechnology Process Monitoring: Essential for monitoring citrate concentrations in cell culture media and fermentation broths during bioprocessing.

Basic Information

Product Name	Anion Standard - Citrate
CAS No.	126-44-3
Molecular Formula	C6H5Na3O7 • 2H2O
Molecular Weight	294.10 g/mol (Dihydrate)
Synonyms	Trisodium Citrate Dihydrate; Sodium Citrate Tribasic Dihydrate; Citric Acid Trisodium Salt Dihydrate; 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, trisodium salt, dihydrate; Natriumcitrat; E331; Citrosodina; Alkalinity Standard
EINECS	205-623-3 (Anhydrous)

Quality Control

Our Anion Standard - Citrate is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including identification, assay, and impurity profiling, to ensure it meets the high-purity requirements for a reliable reference material. Certificates of Analysis (COA) are provided with each shipment, detailing the specific results for traceability and compliance. The product is suitable for use in environments adhering to GMP, ISO 17025, and ISO 9001 standards.

Storage

Preserve in a tightly closed container, protected from light. Store at a controlled room temperature, ideally between 15-25°C (59-77°F). The product is hygroscopic (moisture-sensitive); therefore, the container should be kept in a dry environment and sealed immediately after use to prevent absorption of atmospheric moisture, which could affect concentration and stability.

Specification

Item	Specification
Appearance	White crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (Titration)	≥ 99.0% (on anhydrous basis)
pH (5% solution)	7.5 - 9.0
Water Content (KF)	10.0 - 13.0%
Chloride (Cl)	≤ 0.001%
Sulfate (SO4)	≤ 0.005%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.