Description

4-Hydroxy-3-(4-Methylphenyl)-1,8-Naphthyridin-2(1H)-One is a specialized heterocyclic organic compound belonging to the naphthyridine class, serving as a key advanced intermediate in modern chemical synthesis. Its value lies in its unique fused-ring structure, which provides a versatile scaffold for developing novel active pharmaceutical ingredients (APIs) and functional materials. This product is essential for research and development chemists in the pharmaceutical, agrochemical, and material science industries seeking to create new molecules with targeted properties.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in therapeutic areas requiring complex heterocyclic cores.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the naphthyridine structure can contribute to specific biological activity.
• Material Science Precursor: Serves as a starting material for creating organic electronic components, ligands for catalysts, or specialty dyes and pigments.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for methodological studies and the exploration of new chemical reactions.
• Fine Chemical Synthesis: Acts as a versatile intermediate for custom synthesis projects, enabling the production of complex, high-value specialty chemicals.

Basic Information

Product Name	4-Hydroxy-3-(4-Methylphenyl)-1,8-Naphthyridin-2(1H)-One
CAS No.	67862-30-0
Molecular Formula	C₁₅H₁₂N₂O₂
Molecular Weight	252.27 g/mol
Synonyms	3-(p-Tolyl)-1,8-naphthyridin-2-ol; 3-(4-Methylphenyl)-1,8-naphthyridin-2-ol; 4-Hydroxy-3-(4-methylphenyl)-1,8-naphthyridin-2(1H)-one; 2(1H)-Naphthyridinone, 4-hydroxy-3-(4-methylphenyl)-; 3-(4-Methylphenyl)-1,8-naphthyridin-2(1H)-one; 4-Hydroxy-3-(p-tolyl)-1,8-naphthyridin-2(1H)-one
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-3-(4-Methylphenyl)-1,8-Naphthyridin-2(1H)-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling. A Certificate of Analysis (COA) detailing identity, purity, and related substances is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.