Description

(E)-m-(Trifluoromethyl)Cinnamic Acid is a high-purity fluorinated cinnamic acid derivative characterized by its distinct trifluoromethyl substituent on the meta position of the aromatic ring. This compound is a valuable pharmaceutical intermediate and building block in organic synthesis, prized for its ability to impart unique electronic and steric properties to target molecules. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of drug candidates, particularly those targeting metabolic and inflammatory pathways where the trifluoromethyl group enhances bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and plant growth regulators.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display and lighting materials, improving performance characteristics.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, such as Heck reactions, and as a precursor for more complex fluorinated structures in medicinal chemistry.
• Chemical Research: A standard reagent in academic and industrial R&D labs for studying fluorination effects and developing new synthetic methodologies.
• Polymer Modification: Can be incorporated into polymer chains to create specialty polymers with tailored surface properties and chemical resistance.

Basic Information

Product Name	(E)-m-(Trifluoromethyl)Cinnamic Acid
CAS No.	67801-07-4
Molecular Formula	C10H7F3O2
Molecular Weight	216.16 g/mol
Synonyms	(E)-3-[3-(Trifluoromethyl)phenyl]acrylic acid; (E)-3-(3-Trifluoromethylphenyl)-2-propenoic acid; m-(Trifluoromethyl)cinnamic acid; trans-3-(3-Trifluoromethylphenyl)propenoic acid; (E)-3-(3-Trifluoromethylphenyl)acrylic acid; 3-(3-Trifluoromethylphenyl)prop-2-enoic acid; (2E)-3-[3-(Trifluoromethyl)phenyl]prop-2-enoic acid
EINECS	Contact for details

Quality Control

Our (E)-m-(Trifluoromethyl)Cinnamic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP or research use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and incompatible materials. The product is light-sensitive and should be stored away from direct light exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.