Description

3-Quinolinecarboxylic Acid, 1,2,3,4-Tetrahydro-, Ethyl Ester is a high-purity, versatile heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its functionalized quinoline scaffold, which serves as a critical precursor for the development of complex pharmacologically active molecules. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and fine chemical industries seeking to create novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon in the research and synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and other therapeutic areas.
• Agrochemical Research: Used as a building block for developing new active ingredients in herbicides, fungicides, and insecticides, leveraging its heterocyclic structure.
• Fine Chemical Synthesis: Employed in the preparation of complex organic molecules, dyes, and functional materials requiring a tetrahydroquinoline core.
• Ligand and Catalyst Development: Serves as a precursor for nitrogen-containing ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry and for scaling up novel synthetic pathways.

Basic Information

Product Name	3-Quinolinecarboxylic Acid, 1,2,3,4-Tetrahydro-, Ethyl Ester
CAS No.	67752-37-8
Molecular Formula	C₁₂H₁₅NO₂
Molecular Weight	205.25 g/mol
Synonyms	Ethyl 1,2,3,4-Tetrahydroquinoline-3-carboxylate; 1,2,3,4-Tetrahydroquinoline-3-carboxylic Acid Ethyl Ester; Ethyl 1,2,3,4-Tetrahydro-3-quinolinecarboxylate; 3-Carbethoxy-1,2,3,4-tetrahydroquinoline; 3-Quinolinecarboxylic acid, 1,2,3,4-tetrahydro-, ethyl ester; Tetrahydroquinoline-3-carboxylic acid ethyl ester; Ethyl tetrahydroquinoline-3-carboxylate
EINECS	Contact for details

Quality Control

Our 3-Quinolinecarboxylic Acid, 1,2,3,4-Tetrahydro-, Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our commitment to cGMP and ISO principles ensures a reliable supply of material suitable for demanding research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.