Description

(R)-tert-Butanethiosulfinate is a high-purity chiral organosulfur compound, specifically the (R)-enantiomer of tert-butane thiosulfinate. This compound serves as a valuable chiral building block and intermediate in asymmetric synthesis, particularly for the preparation of sulfoxides and other sulfur-containing molecules with defined stereochemistry. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require enantiomerically pure intermediates for the development of active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of enantiomerically pure sulfoxide drugs, such as certain proton pump inhibitors.
• Asymmetric Synthesis: Used as a chiral auxiliary or reagent in stereoselective carbon-sulfur bond-forming reactions.
• Agrochemical Research: Intermediate for developing chiral active ingredients in herbicides, fungicides, and insecticides.
• Ligand and Catalyst Preparation: Building block for synthesizing chiral sulfur-containing ligands for metal-catalyzed reactions.
• Flavor and Fragrance Industry: Potential intermediate for creating specific sulfur-based aroma compounds.
• Material Science: Research component for developing novel chiral polymers or functional materials.

Basic Information

Product Name	(R)-tert-Butanethiosulfinate
CAS No.	67734-35-4
Molecular Formula	C4H10OS2
Molecular Weight	138.25 g/mol
Synonyms	(R)-2-Methyl-2-propanethiosulfinic acid S-ester; (R)-tert-Butyl thiosulfinate; (R)-t-Butanethiosulfinate; (R)-TBTS; (R)-tert-Butylsulfinylsulfane; (R)-2-Methylpropane-2-thiosulfinic acid S-ester; (R)-tert-Butyl sulfoxide sulfide
EINECS	Contact for details

Quality Control

Our (R)-tert-Butanethiosulfinate is produced under strict quality management protocols. Each batch is characterized and tested to ensure high chemical and enantiomeric purity, meeting the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (by HPLC/GC), chiral purity (by Chiral HPLC), and other relevant parameters is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This compound is easily oxidized and light-sensitive. Allow the container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR / NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.