Description

1,4,8,11-Tetraazacyclotetradecane, 1,4,8-Trimethyl- is a functionalized macrocyclic tetraamine ligand, a derivative of cyclam (1,4,8,11-tetraazacyclotetradecane). This compound is valued for its strong and selective chelating properties towards transition metal ions, forming stable coordination complexes. It is primarily utilized in advanced chemical synthesis, catalysis, and materials science research. The product is supplied with a CAS Registry Number of 67707-85-1.

Application

• Coordination Chemistry & Catalyst Synthesis: Serves as a key ligand for constructing homogeneous catalysts used in oxidation, polymerization, and other organic transformations.
• Metal Ion Sequestration & Separation: Employed in the development of selective chelating agents for metal recovery, purification, and environmental remediation processes.
• Biomimetic & Medicinal Chemistry Research: Used to model metalloenzyme active sites and in the synthesis of potential therapeutic agents, including MRI contrast agent precursors.
• Materials Science: A building block for creating functionalized surfaces, metal-organic frameworks (MOFs), and other supramolecular assemblies with tailored properties.
• Analytical Chemistry: Can be incorporated into sensors or chromatographic supports for the selective detection and separation of specific metal cations.

Basic Information

Product Name	1,4,8,11-Tetraazacyclotetradecane, 1,4,8-Trimethyl-
CAS No.	67707-85-1
Molecular Formula	C11H26N4
Molecular Weight	214.35 g/mol
Synonyms	1,4,8-Trimethyl-1,4,8,11-tetraazacyclotetradecane; 1,4,8-Trimethylcyclam; 1,4,8-Trimethyl-1,4,8,11-tetraazacyclotetradecane; TMCyclam; 1,4,8-Trimethyl-1,4,8,11-tetraazacyclotetradec-11-ane; 1,4,8-Trimethyltetraazacyclotetradecane; Trimethylcyclam; 1,4,8,11-Tetraazacyclotetradecane, 1,4,8-trimethyl-
EINECS	Contact for details

Quality Control

Our 1,4,8,11-Tetraazacyclotetradecane, 1,4,8-Trimethyl- is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided, confirming compliance with agreed specifications. We support custom synthesis and can tailor purity grades to meet specific research or industrial application requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.