Description

4-(Aminomethyl)Benzoic Acid Hydrochloride is a high-purity organic salt derivative of para-aminomethylbenzoic acid, widely recognized for its role as a key pharmaceutical intermediate and versatile building block in organic synthesis. Its primary value lies in providing a protected amine functionality in a crystalline, stable hydrochloride salt form, which is crucial for precise chemical transformations. This compound is essential for research and production facilities in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs), peptide mimetics, and complex organic molecules.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of various active pharmaceutical ingredients (APIs), including protease inhibitors and other therapeutic agents.
• Peptide Chemistry: Used as a protected amino acid derivative for the solid-phase and solution-phase synthesis of peptides and peptide mimetics.
• Organic Synthesis: Serves as a versatile precursor for introducing the 4-(aminomethyl)benzoic acid moiety into more complex molecular architectures via amide coupling or other reactions.
• Linker Molecule: Employed in bioconjugation and the development of antibody-drug conjugates (ADCs) due to its carboxylic acid and amine functional groups.
• Agrochemical Synthesis: Acts as an intermediate in the production of certain herbicides, fungicides, and plant growth regulators.
• Material Science: Utilized in the research and development of specialty polymers, dendrimers, and functional organic materials.

Basic Information

Product Name	4-(Aminomethyl)Benzoic Acid Hydrochloride
CAS No.	67688-72-6
Molecular Formula	C8H9NO2 • HCl
Molecular Weight	187.62 g/mol
Synonyms	4-(Aminomethyl)benzoic acid HCl; 4-Carboxybenzylamine hydrochloride; p-(Aminomethyl)benzoic acid hydrochloride; (4-Carboxyphenyl)methanamine hydrochloride; 4-AMBA HCl; 4-(Aminomethyl)benzoic acid monohydrochloride; Benzoic acid, 4-(aminomethyl)-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our 4-(Aminomethyl)Benzoic Acid Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, to meet stringent specifications suitable for pharmaceutical R&D and synthesis. A Certificate of Analysis (COA) detailing identity, purity, and related substances is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed to prevent absorption of atmospheric moisture, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.