Description

8-Bromo-4-Hydroxy-6-Methylquinoline-3-Carboxylic Acid is a high-purity, synthetically valuable quinoline derivative used as a key building block in advanced organic synthesis. This compound matters because it serves as a crucial intermediate for the development of novel pharmaceuticals, agrochemicals, and functional materials, enabling the introduction of specific bromo and carboxylic acid functionalities. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for the synthesis of complex target molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds with quinoline-based structures.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated quinoline core.
• Organic Synthesis Building Block: Employed in medicinal chemistry and material science for constructing complex heterocyclic compounds via cross-coupling and functional group transformations.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chelating ligands or organocatalysts due to its carboxylic acid and heteroatom sites.
• Fluorescent Dye and Sensor Precursor: Utilized in the research and development of quinoline-based fluorescent probes and molecular sensors.

Basic Information

Product Name	8-Bromo-4-Hydroxy-6-Methylquinoline-3-Carboxylic Acid
CAS No.	67643-47-4
Molecular Formula	C12H8BrNO3
Molecular Weight	294.10 g/mol
Synonyms	8-Bromo-4-hydroxy-6-methylquinoline-3-carboxylic acid; 3-Quinolinecarboxylic acid, 8-bromo-4-hydroxy-6-methyl-; 8-Bromo-6-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; 8-Bromo-4-hydroxy-6-methyl-3-quinolinecarboxylic acid; 8-Bromo-4-hydroxy-6-methylquinoline-3-carboxylate; 67643-47-4 (CAS)
EINECS	Contact for details

Quality Control

Our 8-Bromo-4-Hydroxy-6-Methylquinoline-3-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive and should be stored away from direct light exposure. Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.