Description

8-Bromo-4-Hydroxy-6-Methylquinoline-3-Carboxylic Acid Ethyl Ester is a high-purity, synthetically valuable quinoline derivative that serves as a critical building block in advanced organic synthesis. Its functionalized structure makes it an essential intermediate for researchers and manufacturers developing novel active pharmaceutical ingredients (APIs) and specialty fine chemicals. This compound is primarily targeted at the pharmaceutical, agrochemical, and advanced materials research sectors, where precise molecular architecture is paramount.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex quinoline-based drug candidates, particularly those targeting infectious diseases and central nervous system disorders.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides, leveraging its halogenated quinoline core for bioactivity.
• Ligand Synthesis: Serves as a starting material for creating sophisticated chelating agents and catalysts used in asymmetric synthesis and metal-organic frameworks (MOFs).
• Fluorescent Dye & Sensor Development: The quinoline scaffold is utilized in the design of novel fluorescent probes and molecular sensors for analytical chemistry and bio-imaging.
• Material Science: Employed in the synthesis of organic semiconductors and electronic materials due to its conjugated aromatic system.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting medicinal chemistry and heterocyclic compound research.

Basic Information

Product Name	8-Bromo-4-Hydroxy-6-Methylquinoline-3-Carboxylic Acid Ethyl Ester
CAS No.	67643-32-7
Molecular Formula	C₁₄H₁₄BrNO₃
Molecular Weight	324.17 g/mol
Synonyms	Ethyl 8-Bromo-4-hydroxy-6-methylquinoline-3-carboxylate; 8-Bromo-4-hydroxy-6-methyl-3-quinolinecarboxylic Acid Ethyl Ester; 3-Quinolinecarboxylic acid, 8-bromo-4-hydroxy-6-methyl-, ethyl ester; 67643-32-7; 8-Bromo-4-hydroxy-6-methylquinoline-3-carboxylic acid ethyl ester; Ethyl 8-bromo-4-hydroxy-6-methylquinoline-3-carboxylate
EINECS	Contact for details

Quality Control

Our production of 8-Bromo-4-Hydroxy-6-Methylquinoline-3-Carboxylic Acid Ethyl Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support cGMP-compliant manufacturing for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥97.0% (Area %)
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.