Description

8-tert-Butyl Quinoline is a specialized quinoline derivative characterized by a bulky tert-butyl substituent at the 8-position. This structural feature imparts unique steric and electronic properties, making it a valuable intermediate in advanced organic synthesis and materials science. It is primarily utilized by research and development chemists in the pharmaceutical, agrochemical, and specialty chemical industries for applications requiring high-purity, custom-built molecular frameworks.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system and anti-infective therapies.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, where the quinoline core contributes to biological activity.
• Ligand and Catalyst Development: Acts as a precursor for nitrogen-containing ligands in transition metal catalysis, useful in asymmetric synthesis and polymerization processes.
• Organic Electronic Materials: Investigated as a component in the development of organic light-emitting diodes (OLEDs) and charge-transport materials due to its electron-accepting quinoline structure.
• Corrosion Inhibitor Formulation: Employed in research for high-performance corrosion inhibitors in industrial fluids and coatings.
• Dye and Pigment Intermediate: Functions as a synthetic intermediate for specialized quinoline-based dyes and colorants.

Basic Information

Product Name	8-tert-Butyl Quinoline
CAS No.	67634-06-4
Molecular Formula	C₁₃H₁₅N
Molecular Weight	185.27 g/mol
Synonyms	8-(1,1-Dimethylethyl)quinoline; 8-(tert-Butyl)quinoline; Quinoline, 8-(1,1-dimethylethyl)-; 8-t-Butylquinoline; 8-tert-Butylchinolin (German); 8-tert-Butylquinoleine
EINECS	Contact for details

Quality Control

Our 8-tert-Butyl Quinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets exacting research and industrial standards. Comprehensive Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.