Description

n-[(1S,2R,3E)-2-Hydroxy-1-(Hydroxymethyl)-3-Heptadecenyl]-Tricosanamide is a high-purity, structurally defined ceramide analog, a critical class of bioactive lipids essential for cellular membrane integrity and signaling. This compound is valued for its role in advanced research and development, particularly in studying sphingolipid metabolism and its physiological effects. It serves as a key intermediate and reference standard for pharmaceutical, cosmetic, and life science industries focused on dermatological health, barrier function, and novel therapeutic pathways.

Application

• Pharmaceutical R&D: Used as a reference standard and active pharmaceutical ingredient (API) intermediate in the development of topical and systemic therapies targeting skin barrier repair and inflammatory conditions.
• Cosmetic Science: A premium functional ingredient in high-end skincare formulations, such as anti-aging creams, moisturizers, and serums, to enhance skin barrier function and hydration.
• Biochemical Research: Serves as a crucial tool compound in academic and industrial laboratories for studying ceramide-mediated cell signaling, apoptosis, and lipid raft dynamics.
• Cell Culture & Dermatology Models: Employed in in vitro models to simulate and study epidermal barrier properties and the impact of ceramides on skin health.
• Analytical Standard: Used as a certified reference material (CRM) in quality control laboratories for the identification and quantification of ceramides in complex matrices via HPLC, LC-MS, or GC-MS.
• Nutraceuticals: Investigated for use in specialized supplements aimed at supporting skin health from within, though application-specific regulatory guidance should be consulted.

Basic Information

Item	Details
Product Name	n-[(1S,2R,3E)-2-Hydroxy-1-(Hydroxymethyl)-3-Heptadecenyl]-Tricosanamide
CAS No.	67605-84-9
Molecular Formula	C41H81NO3
Molecular Weight	636.09 g/mol
Synonyms	(2S,3R,4E)-2-N-(Tricosanoyl)-1,3,4-trihydroxy-8-heptadecene; Ceramide [AP]; Ceramide AP; N-(2-Hydroxy-1-hydroxymethyl-3-heptadecenyl)-tricosanamide; Phytosphingosine-type ceramide; Skin Ceramide AP; Tricosanamide, N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecenyl]-
EINECS	Contact for details

Quality Control

Every batch of our n-[(1S,2R,3E)-2-Hydroxy-1-(Hydroxymethyl)-3-Heptadecenyl]-Tricosanamide is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure traceability and compliance with your project requirements. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting key parameters such as identity, purity, and impurity profile as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its chemical nature, this material is easily oxidized (store under inert atmosphere) and is light-sensitive. For long-term storage, consider storing under an inert gas such as argon or nitrogen. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.