Description

trans-(1R,2R)N,N'-Dimethyl-Cyclohexane-1,2-Diamine is a high-purity, chiral diamine ligand and building block of significant importance in asymmetric synthesis. Its rigid cyclohexane backbone and specific stereochemistry make it a highly effective catalyst and chiral auxiliary for producing enantiomerically pure compounds. This product is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereocontrol in their synthetic processes.

Application

• Asymmetric Catalysis: As a privileged chiral ligand for transition metal-catalyzed reactions, including hydrogenation, hydrosilylation, and conjugate addition.
• Pharmaceutical Intermediates: Key building block in the synthesis of active pharmaceutical ingredients (APIs) requiring high enantiomeric excess.
• Agrochemical Synthesis: Used in the production of chiral herbicides, fungicides, and pesticides.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances.
• Organocatalysis: Serves as a catalyst or co-catalyst in metal-free asymmetric transformations.
• Polymer Chemistry: Can be utilized as a monomer or chain modifier for creating polymers with specific stereoregularity.
• Academic & Industrial R&D: A valuable tool for method development and discovery chemistry in research laboratories.

Basic Information

Item	Details
Product Name	trans-(1R,2R)N,N'-Dimethyl-Cyclohexane-1,2-Diamine
CAS No.	67579-81-1
Molecular Formula	C8H18N2
Molecular Weight	142.24 g/mol
Synonyms	(1R,2R)-N,N'-Dimethyl-1,2-cyclohexanediamine; (1R,2R)-N,N'-Dimethylcyclohexane-1,2-diamine; (1R,2R)-DMCHD; trans-N,N'-Dimethyl-(1R,2R)-diaminocyclohexane; (R,R)-N,N'-Dimethyl-1,2-diaminocyclohexane; (R,R)-DACH-N,N'-dimethyl; (1R,2R)-1,2-Diamino-N,N'-dimethylcyclohexane; Jacobsen's Ligand Derivative
EINECS	Contact for details

Quality Control

Our trans-(1R,2R)N,N'-Dimethyl-Cyclohexane-1,2-Diamine is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical and enantiomeric purity, meeting the exacting standards required for advanced synthetic applications. Certificates of Analysis (COA) with detailed specifications for identity, assay, and enantiomeric excess are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to exclude moisture. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Enantiomeric Excess (ee)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.