Description

8-Iodo-3-Nitro-1-Naphthoic Acid is a halogenated and nitrated naphthoic acid derivative, serving as a versatile and high-value synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both iodine and nitro functional groups on the naphthalene core, makes it a critical building block for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research institutions and industrial R&D departments focused on pharmaceuticals, agrochemicals, and materials science.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting specific receptors or requiring halogenated aromatic systems.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and pesticides where the iodine atom can be leveraged for further functionalization or to influence bioactivity.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Sonogashira) and nucleophilic aromatic substitution due to the reactive iodine substituent.
• Dye and Pigment Chemistry: Serves as a starting material for synthesizing specialized naphthalene-based dyes and functional pigments.
• Material Science: Investigated for the development of organic semiconductors, liquid crystals, and other advanced organic electronic materials.
• Chemical Research & Development: A valuable reagent for academic and industrial research exploring new synthetic methodologies and complex molecule construction.

Basic Information

Product Name	8-Iodo-3-Nitro-1-Naphthoic Acid
CAS No.	67522-37-6
Molecular Formula	C11H6INO4
Molecular Weight	343.08 g/mol
Synonyms	1-Naphthoic acid, 8-iodo-3-nitro-; 3-Nitro-8-iodo-1-naphthoic acid; 8-Iodo-3-nitronaphthalene-1-carboxylic acid; NSC 403796; 67522-37-6; 8-Iodo-3-nitro-1-naphthalenecarboxylic acid
EINECS	Contact for details

Quality Control

Our 8-Iodo-3-Nitro-1-Naphthoic Acid is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and packaging should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.