Description

Racemic-(1R,2R)-Ethyl 2'-Oxospiro[Cyclopropane-1,3'-Indoline]-2-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic indoline scaffold. This compound is of significant value for medicinal chemistry research and development, serving as a versatile building block for synthesizing novel bioactive molecules. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel therapeutic targets.
• Asymmetric Synthesis: Serves as a precursor or template in the development of stereoselective synthetic routes.
• Chemical Biology Probes: Utilized in the design and creation of molecular probes for studying biological pathways and protein interactions.
• Academic Research: Employed in university and institutional labs for methodological development in organic and heterocyclic chemistry.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical innovation.

Basic Information

Product Name	Racemic-(1R,2R)-Ethyl 2'-Oxospiro[Cyclopropane-1,3'-Indoline]-2-Carboxylate
CAS No.	67487-95-0
Molecular Formula	C14H15NO3
Molecular Weight	245.27 g/mol
Synonyms	Ethyl 2'-oxospiro[cyclopropane-1,3'-indoline]-2-carboxylate; (±)-(1R,2R)-Ethyl 2'-oxospiro[cyclopropane-1,3'-indoline]-2-carboxylate; Spiro[cyclopropane-1,3'-indoline]-2-carboxylic acid, 2'-oxo-, ethyl ester, (1R,2R)-rel-; Ethyl (1R,2R)-2'-oxospiro[cyclopropane-1,3'-indoline]-2-carboxylate (racemic); 2'-Oxospiro[cyclopropane-1,3'-indoline]-2-carboxylic acid ethyl ester; CAS 67487-95-0
EINECS	Contact for details

Quality Control

Our Racemic-(1R,2R)-Ethyl 2'-Oxospiro[Cyclopropane-1,3'-Indoline]-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP guidelines for advanced intermediates, ensuring reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.