Description

1-Mercapto-4-Phenyl-4H-[1,2,4]Triazolo[4,3-A]Quinazolin-5-One is a complex heterocyclic compound featuring a fused quinazolinone and triazole ring system with a phenyl substituent and a thiol group. This unique molecular architecture makes it a valuable synthetic intermediate and a scaffold of significant interest in advanced organic and medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key building block for synthesizing novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, or oncology.
• Agrochemical Research: Used as a precursor in the development of new herbicides, fungicides, or insecticides, leveraging its heterocyclic core for bioactivity.
• Chemical Biology Probe: Acts as a scaffold for creating molecular probes to study enzyme function or protein-protein interactions due to its potential for selective binding.
• Material Science Research: Investigated as a monomer or additive for creating specialized polymers with unique thermal or electronic properties.
• Academic & Institutional R&D: Employed in universities and research institutes for methodological studies in heterocyclic chemistry and reaction mechanism exploration.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules on a gram to kilogram scale.

Basic Information

Product Name	1-Mercapto-4-Phenyl-4H-[1,2,4]Triazolo[4,3-A]Quinazolin-5-One
CAS No.	67442-90-4
Molecular Formula	C₁₆H₁₀N₄OS
Molecular Weight	306.34 g/mol
Synonyms	4-Phenyl-1-mercapto-4H-[1,2,4]triazolo[4,3-a]quinazolin-5-one; 1-Mercapto-4-phenyl-[1,2,4]triazolo[4,3-a]quinazolin-5(4H)-one; [1,2,4]Triazolo[4,3-a]quinazolin-5-one, 1-mercapto-4-phenyl-4H-; 4H-[1,2,4]Triazolo[4,3-a]quinazolin-5-one, 1-mercapto-4-phenyl-; 67442-90-4 (CAS); MTQO (abbreviation); 4-Phenyl-1-thiol-4H-[1,2,4]triazolo[4,3-a]quinazolin-5-one
EINECS	Contact for details

Quality Control

Our 1-Mercapto-4-Phenyl-4H-[1,2,4]Triazolo[4,3-A]Quinazolin-5-One is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.