Description

(R)-1-Phenylethylhydroxylamine is a high-value chiral amine building block and resolving agent. This compound matters for its critical role in asymmetric synthesis, enabling the production of enantiomerically pure pharmaceuticals and fine chemicals. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for chiral resolution and as a precursor to advanced intermediates.

Application

• Chiral Resolution Agent: Used for the separation of racemic mixtures of carboxylic acids and other chiral compounds.
• Pharmaceutical Intermediate: A key precursor in the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs), particularly for CNS and cardiovascular drugs.
• Asymmetric Synthesis: Serves as a chiral auxiliary or ligand in catalytic asymmetric reactions to induce stereoselectivity.
• Agrochemical Synthesis: Employed in the production of chiral herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Used in the manufacture of specialty chemicals, flavors, and fragrances requiring high optical purity.
• Research & Development: A valuable tool in academic and industrial R&D for method development in organic and medicinal chemistry.

Basic Information

Product Name	(R)-1-Phenylethylhydroxylamine
CAS No.	67377-55-3
Molecular Formula	C8H11NO
Molecular Weight	137.18 g/mol
Synonyms	(R)-α-Methylbenzylhydroxylamine; (R)-1-Phenylethylamine, N-hydroxy-; (R)-N-Hydroxy-α-methylbenzylamine; (R)-N-Hydroxy-1-phenylethylamine; (R)-N-Hydroxyamphetamine; (R)-1-Phenylethylhydroxylamine; (R)-PEHA; (R)-(-)-1-Phenylethylhydroxylamine
EINECS	Contact for details

Quality Control

Our (R)-1-Phenylethylhydroxylamine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting standards for research and industrial use. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee product identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to prevent oxidation and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.